Piriformis Syndrome Although all cases of sciatica are caused by irritation of the sciatic nerve, not all cases come from the back. The piriformis muscle is a small muscle that sits deep in the buttock. Read More Osteopathy, Hip, Upper Leg, Knee, Lower Back, Pelvis, BackFreya Baskeyfield7 April 2021Flitwick Osteopathic Clinicback, buttock, exercise, hip, muscular, nerve, pain, pelvis, pins and needles, piriformis, pregnancy, relax, sciatica